PIM 3 kinase, a proto-oncogene product, regulates phosphorylation of the measles virus nucleoprotein tail domain at Ser 479 and Ser 510.
Sign Up to like & getrecommendations! Published in 2020 at "Biochemical and biophysical research communications"
DOI: 10.1016/j.bbrc.2020.06.002
Abstract: The tail domain of the measles virus (MeV) N protein is typically phosphorylated at S479 and S510. However, the protein kinase responsible for this phosphorylation has not been identified. To identify the protein kinase responsible,… read more here.
Keywords: tail domain; kinase; measles virus; pim kinase ... See more keywords
Dynamic intramolecular regulation of the histone chaperone nucleoplasmin controls histone binding and release
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DOI: 10.1038/s41467-017-02308-3
Abstract: Nucleoplasmin (Npm) is a highly conserved histone chaperone responsible for the maternal storage and zygotic release of histones H2A/H2B. Npm contains a pentameric N-terminal core domain and an intrinsically disordered C-terminal tail domain. Though intrinsically… read more here.
Keywords: tail domain; histone binding; histone; histone chaperone ... See more keywords
Ligation of free HMGB1 to TLR2 in the absence of ligand is negatively regulated by the C-terminal tail domain
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DOI: 10.1186/s10020-018-0021-x
Abstract: BackgroundHigh mobility group box 1 (HMGB1) protein is a central endogenous inflammatory mediator contributing to the pathogenesis of several inflammatory disorders. HMGB1 interacts with toll-like receptors (TLRs) but contradictory evidence regarding its identity as a TLR2… read more here.
Keywords: hmgb1; tlr2; negatively regulated; tail domain ... See more keywords
Mutations in the tail domain of MYH3 contributes to atrial septal defect
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DOI: 10.1371/journal.pone.0230982
Abstract: Atrial septal defect (ASD) is one of the most common congenital heart defects diagnosed in children. Sarcomeric genes has been attributed to ASD and knockdown of MYH3 functionally homologues gene in chick models indicated abnormal… read more here.
Keywords: myh3; atrial septal; domain myh3; septal defect ... See more keywords