Absence of familiarity triggers hallmarks of autism in mouse model through aberrant tail-of-striatum and prelimbic cortex signaling
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DOI: 10.1016/j.neuron.2022.02.001
Abstract: Autism spectrum disorder (ASD) involves genetic and environmental components. The underlying circuit mechanisms are unclear, but behaviorally, aversion toward unfamiliarity, a hallmark of autism, might be involved. Here, we show that in Shank3ΔC/ΔC ASD model… read more here.
Keywords: exposure; mice; tail striatum; prelimbic cortex ... See more keywords