Effectiveness comparisons of G-protein biased and unbiased mu opioid receptor ligands in warm water tail-withdrawal and drug discrimination in male and female rats
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DOI: 10.1016/j.neuropharm.2019.01.020
Abstract: &NA; One emerging strategy to address the opioid crisis is the development of mu opioid receptor (MOR) ligands that preferentially signal the G‐protein vs. &bgr;‐arrestin pathway. The present study compared the relative potency and effectiveness… read more here.
Keywords: tail withdrawal; protein biased; stimulus effects; mor ... See more keywords