Fine Tuning of Antibiotic Activity by a Tailoring Hydroxylase in a Trans‐AT Polyketide Synthase Pathway
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DOI: 10.1002/cbic.201800036
Abstract: The addition or removal of hydroxy groups modulates the activity of many pharmacologically active biomolecules. It can be integral to the basic biosynthetic factory or result from associated tailoring steps. For the anti‐MRSA antibiotic mupirocin,… read more here.
Keywords: fine tuning; tailoring hydroxylase; activity tailoring; tuning antibiotic ... See more keywords