Tailoring the Physicochemical Properties of Antimicrobial Peptides onto Thiazole-based γ-Peptide Foldamer.
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DOI: 10.1021/acs.jmedchem.0c00077
Abstract: Antimicrobial peptides (AMPs) are amphipathic molecules displaying broad-spectrum bactericidal activity providing opportunities to develop new generation of antibiotics. However their use is limited either by poor metabolic stability or high hemolytic activity. We herein addressed… read more here.
Keywords: physicochemical properties; thiazole based; tailoring physicochemical; based peptide ... See more keywords