The three-tails approach as a new strategy to improve selectivity of action of sulphonamide inhibitors against tumour-associated carbonic anhydrase IX and XII
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DOI: 10.1080/14756366.2022.2053526
Abstract: Abstract Human (h) carbonic anhydrase (CAs, EC 4.2.1.1) isoforms IX and XII were recently confirmed as anticancer targets against solid hypoxic tumours. The “three-tails approach” has been proposed as an extension of the forerunner “tail”… read more here.
Keywords: carbonic anhydrase; tumour associated; selectivity; tails approach ... See more keywords