Articles with "tak1 inhibitor" as a keyword



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Differences in the sensitivity of classically and alternatively activated macrophages to TAK1 inhibitor-induced necroptosis

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Published in 2020 at "Cancer Immunology, Immunotherapy"

DOI: 10.1007/s00262-020-02623-7

Abstract: Controlling the balance of pro-inflammatory M1 versus anti-inflammatory M2 macrophages may have paramount therapeutic benefit in cardiovascular diseases, infections, cancer and chronic inflammation. The targeted depletion of different macrophage populations provides a therapeutic option to… read more here.

Keywords: inhibitor induced; inhibitor; induced necroptosis; sensitivity ... See more keywords