Differential Use of Rap1 Effectors for Integrin Activation in Platelets and Lymphocytes
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DOI: 10.1182/blood-2020-142720
Abstract: Rap1 is a major convergence point of the platelet and lymphocyte signaling pathways that result in talin1 binding to the integrin β-cytoplasmic domain and consequent integrin activation, effective hemostasis and immune functions. The nature of… read more here.
Keywords: integrin activation; r35e r118e; rap1; activation ... See more keywords