The formation of estrogen-like tamoxifen metabolites and their influence on enzyme activity and gene expression of ADME genes
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DOI: 10.1007/s00204-017-2147-y
Abstract: Tamoxifen, a standard therapy for breast cancer, is metabolized to compounds with anti-estrogenic as well as estrogen-like action at the estrogen receptor. Little is known about the formation of estrogen-like metabolites and their biological impact.… read more here.
Keywords: tamoxifen bisphenol; tamoxifen; activity; estrogen like ... See more keywords