CYP2D6 genotype and endoxifen plasma concentration do not predict hot flash severity during tamoxifen therapy
Sign Up to like & getrecommendations! Published in 2018 at "Breast Cancer Research and Treatment"
DOI: 10.1007/s10549-018-4876-x
Abstract: PurposeTamoxifen is frequently prescribed to prevent breast cancer recurrence. Tamoxifen is a prodrug and requires bioactivation by CYP2D6. Tamoxifen use is often limited by adverse effects including severe hot flashes. There is paucity of prospectively… read more here.
Keywords: flash severity; endoxifen; tamoxifen therapy; hot flash ... See more keywords
Retinal structural changes in patients receiving tamoxifen therapy by spectral-domain optical coherence tomography
Sign Up to like & getrecommendations! Published in 2020 at "Cutaneous and Ocular Toxicology"
DOI: 10.1080/15569527.2020.1734816
Abstract: Abstract Purpose: To evaluate choroidal thickness, ganglion cell complex (GCC) and photoreceptor outer segment (PROS) length were measured in patients with breast cancer undergoing tamoxifen therapy, using spectral-domain optical coherence tomography (SD-OCT); results were compared… read more here.
Keywords: domain optical; choroidal thickness; spectral domain; therapy ... See more keywords