Downregulation of LINC00894-002 Contributes to Tamoxifen Resistance by Enhancing the TGF-β Signaling Pathway
Sign Up to like & getrecommendations! Published in 2018 at "Biochemistry (Moscow)"
DOI: 10.1134/s0006297918050139
Abstract: Tamoxifen is a widely used personalized medicine for estrogen receptor (ER)-positive breast cancer, but approximately 30% of patients receiving the treatment relapse due to tamoxifen resistance (TamR). Recently, several reports have linked lncRNAs to cancer… read more here.
Keywords: linc00894 002; group; tamoxifen resistance; signaling pathway ... See more keywords
Matrix Metalloproteinase-1 (MMP1) Upregulation through Promoter Hypomethylation Enhances Tamoxifen Resistance in Breast Cancer
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DOI: 10.3390/cancers14051232
Abstract: Simple Summary Cancer recurrence caused by tamoxifen resistance hampers chemotherapy in breast cancer patients. The reasons behind the resistance were investigated by screening epigenetically regulated genes through analysis of methylation data from tamoxifen-resistant MCF-7 cells.… read more here.
Keywords: tamr; mmp1; breast cancer; resistance ... See more keywords