Copper-catalyzed tandem cyclization and vinylation for the synthesis of 2-trifluoromethyl benzofurans
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Fluorine Chemistry"
DOI: 10.1016/j.jfluchem.2019.109418
Abstract: Abstract A copper-catalyzed tandem cyclization and vinylation of 2-chloro-1-(2-bromoaryl)-3,3,3-trifluoropropenes with KOH has been developed for the synthesis of 2-trifluoromethyl benzofuran derivatives. The reaction involves dual C O bonds formation and hydroarylation of aryl trifluoropropynes. This… read more here.
Keywords: tandem cyclization; cyclization vinylation; catalyzed tandem; synthesis trifluoromethyl ... See more keywords
The synthesis of perfluoroalkylated indolizines via tandem cyclization/aromatization
Sign Up to like & getrecommendations! Published in 2021 at "Journal of Fluorine Chemistry"
DOI: 10.1016/j.jfluchem.2021.109900
Abstract: Abstract The incorporation of a perfluoroalkyl group into heterocycles has received increasing attention. Herein we describe the synthesis of perfluoroalkylated indolizines via a tandem cyclization/aromatization process under mild conditions. In contrast to previous synthetic methods,… read more here.
Keywords: tandem cyclization; cyclization aromatization; indolizines via; via tandem ... See more keywords
Divergent Conversion of Double Isocyanides with Alkenyl Bromide to Polysubstituted Pyrroles and 4-Imino-4,5-dihydropyrrolo[3,4-b]pyrrol-6(1H)-one Derivatives by Pd-Catalyzed Tandem Cyclization Reactions.
Sign Up to like & getrecommendations! Published in 2022 at "Organic letters"
DOI: 10.1021/acs.orglett.1c04146
Abstract: Herein a novel and concise approach to pyrrole skeletons via Pd-catalyzed tandem cyclization reactions is investigated. The substrates for the transformation could be readily prepared by phosphoric acid-catalyzed Ugi reactions with available starting materials. In… read more here.
Keywords: catalyzed tandem; cyclization reactions; divergent conversion; tandem cyclization ... See more keywords
Copper(ii)-catalyzed tandem cyclization for the synthesis of benzo[d][1,3]thiazin-2-yl phosphonates involving C–P and C–S bond formation
Sign Up to like & getrecommendations! Published in 2020 at "RSC Advances"
DOI: 10.1039/d0ra06671k
Abstract: A copper(II)-catalyzed, high-efficiency and atom-economical synthesis of valuable organophosphorus compounds via tandem cyclization of o-alkynylphenyl isothiocyanates with phosphites is described. This protocol, having a good functional-group compatibility, provides a simple and direct pathway to organophosphorus… read more here.
Keywords: tandem cyclization; cyclization; catalyzed tandem; cyclization synthesis ... See more keywords
I2-mediated Csp2–P bond formation via tandem cyclization of o-alkynylphenyl isothiocyanates with organophosphorus esters
Sign Up to like & getrecommendations! Published in 2022 at "RSC Advances"
DOI: 10.1039/d2ra03072a
Abstract: A novel, I2-mediated tandem cyclization of o-alkynylphenyl isothiocyanates with organophosphorus esters has been developed under mild conditions. Different kinds of 4H-benzo[d][1,3]thiazin-2-ylphosphonate could be synthesized in moderate to excellent yields. This method has the advantages of… read more here.
Keywords: isothiocyanates organophosphorus; alkynylphenyl isothiocyanates; organophosphorus esters; cyclization alkynylphenyl ... See more keywords
Synthesis of 2-Pyrrolidinone Derivatives via N-Heterocyclic Carbene Catalyzed Radical Tandem Cyclization/Coupling Reaction
Sign Up to like & getrecommendations! Published in 2023 at "Organic Chemistry Frontiers"
DOI: 10.1039/d3qo00544e
Abstract: Herein, a practical, convenient and facile protocol to construct highly functionalized 2-pyrrolidinone enabled by N-Heterocyclic Carbene(NHC)-catalyzed radical tandem cyclization has been developed (30 examples, up to 94% yield). This method... read more here.
Keywords: radical tandem; catalyzed radical; tandem cyclization; pyrrolidinone ... See more keywords