Structural basis of DEPTOR to recognize phosphatidic acid using its tandem DEP domains.
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DOI: 10.1016/j.jmb.2021.166989
Abstract: DEP domain containing mTOR-interacting protein (DEPTOR) plays pivotal roles in regulating metabolism, growth, autophagy and apoptosis by functions as an endogenous inhibitor of mTOR signaling pathway. Activated by phosphatidic acid, a second messenger in mTOR… read more here.
Keywords: acid using; dep domains; tandem dep; phosphatidic acid ... See more keywords