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   Articles with "tandem lesions" as a keyword



Functional and Safety Outcomes of Carotid Artery Stenting and Mechanical Thrombectomy for Large Vessel Occlusion Ischemic Stroke With Tandem Lesions

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recommendations! Published in 2023 at "JAMA Network Open"

DOI: 10.1001/jamanetworkopen.2023.0736

Abstract: Key Points Question Is carotid artery stenting (CAS) during mechanical thrombectomy (MT) associated with improved functional outcome without an increase in hemorrhagic rates in patients with large vessel occlusion ischemic stroke with tandem lesions, defined… read more here.

Keywords: large vessel; tandem lesions; occlusion; carotid artery ... See more keywords

Tandem lesions arising from 5-(uracilyl)methyl peroxyl radical addition to guanine: Product analysis and mechanistic studies.

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recommendations! Published in 2019 at "Chemical research in toxicology"

DOI: 10.1021/acs.chemrestox.9b00407

Abstract: The reaction of hydroxyl radical (HO●) with thymine in DNA generates 5-(uracilyl)-methyl radicals (T●) and the corresponding methylperoxyl radical (TOO●) in the presence of O2, which in turn propagates damage by reacting with a vicinal… read more here.

Keywords: tandem lesions; guanine; uracilyl methyl; addition guanine ... See more keywords

Endovascular treatment of acute tandem lesions in patients with mild anterior circulation stroke

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recommendations! Published in 2022 at "Journal of NeuroInterventional Surgery"

DOI: 10.1136/jnis-2022-019239

Abstract: Background In patients with mild strokes the risk–benefit ratio of endovascular treatment (EVT) for tandem lesions has yet to be evaluated outside of current guideline recommendations. This study investigates the frequency as well as procedural… read more here.

Keywords: tandem lesions; patients mild; endovascular treatment; treatment ... See more keywords

Tandem Lesions in Anterior Circulation Stroke

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recommendations! Published in 2021 at "Stroke"

DOI: 10.1161/strokeaha.120.031797

Abstract: Supplemental Digital Content is available in the text. Background and Purpose: Tandem lesions in the anterior circulation account for up to 30% of all large vessel occlusion strokes. The optimal periprocedural approach in these lesions… read more here.

Keywords: lesions anterior; anterior circulation; treatment; ica ... See more keywords

Safety, efficacy and timing of antithrombotic therapy in emergency stenting of acute stroke patients with tandem lesions, German multicenter data-analysis

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recommendations! Published in 2025 at "Frontiers in Neurology"

DOI: 10.3389/fneur.2025.1554691

Abstract: Background Antithrombotic therapy of acute stroke patients with tandem lesions and emergent carotid artery stenting (CAS) is still a matter of controversial debates. The lack of evidence from dedicated studies favors a variety of clinical… read more here.

Keywords: stroke; patients tandem; antithrombotic therapy; tandem lesions ... See more keywords