A WW Tandem-Mediated Dimerization Mode of SAV1 Essential for Hippo Signaling
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DOI: 10.1016/j.celrep.2020.108118
Abstract: SUMMARY The canonical mammalian Hippo pathway contains a core kinase signaling cascade requiring upstream MST to form a stable complex with SAV1 in order to phosphorylate the downstream LATS/MOB complex. Though SAV1 dimerization is essential… read more here.
Keywords: hippo; mediated dimerization; dimerization; tandem mediated ... See more keywords