Recombinant nanobody against MUC1 tandem repeats inhibits growth, invasion, metastasis and vascularization of spontaneous mouse mammary tumors.
Sign Up to like & getrecommendations! Published in 2021 at "Molecular oncology"
DOI: 10.1002/1878-0261.13123
Abstract: Alteration in glycosylation pattern of MUC1 mucin tandem repeats during carcinomas has been shown to negatively affect adhesive properties of malignant cells and enhance tumor invasiveness and metastasis. In addition, MUC1 overexpression is closely interrelated… read more here.
Keywords: muc1; nanobody; muc1 tandem; tandem repeats ... See more keywords
Variable number of tandem repeats of 9 Plasmodium vivax genes among Southeast Asian isolates.
Sign Up to like & getrecommendations! Published in 2017 at "Acta tropica"
DOI: 10.1016/j.actatropica.2017.01.013
Abstract: The variable number of tandem repeats (VNTRs) provides valuable information about both the functional and evolutionary aspects of genetic diversity. Comparative analysis of 3 Plasmodium falciparum genomes has shown that more than 9% of its… read more here.
Keywords: vivax genes; southeast asian; variable number; tandem repeats ... See more keywords
Tandem Repeats and Repeatomes: Delving Deeper into the ‘Dark Matter’ of Genomes
Sign Up to like & getrecommendations! Published in 2018 at "EBioMedicine"
DOI: 10.1016/j.ebiom.2018.04.004
Abstract: The understanding of human biology and diseases, and the practice (below the threshold for HD) there was an association between CAG reof modernmedicine, is being transformed by genomics. The sequencing of the human genome (from… read more here.
Keywords: dark matter; tandem repeat; human genome; tandem repeats ... See more keywords
Short Tandem Repeats in plants: Genomic distribution and function prediction
Sign Up to like & getrecommendations! Published in 2021 at "Electronic Journal of Biotechnology"
DOI: 10.1016/j.ejbt.2020.12.003
Abstract: Abstract Background Short Tandem repeats (STRs) existed as popular elements in both eukaryotic and prokaryotic genomes. Results In this study, we analyzed the characteristics, distributions, and motif features of STRs within whole-genomes of 140 plant… read more here.
Keywords: short tandem; long strs; tandem repeats; repeats plants ... See more keywords
LEPStr: A database for Mycobacterium leprae short tandem repeats
Sign Up to like & getrecommendations! Published in 2020 at "Informatics in Medicine Unlocked"
DOI: 10.1016/j.imu.2020.100322
Abstract: Abstract Short tandem repeats are short arrays of nucleotide sequences, and they have vital roles in many biological processes, including modulation of transcription, enhancement of gene expression, adaptation to a particular environment, and link to… read more here.
Keywords: short tandem; repeat; database; mycobacterium leprae ... See more keywords
Evolution patterns of Peg3 and H19-ICR.
Sign Up to like & getrecommendations! Published in 2018 at "Genomics"
DOI: 10.1016/j.ygeno.2018.11.025
Abstract: Mammalian imprinted domains are regulated through small genomic regions termed Imprinting Control Regions (ICRs). In the current study, the evolution patterns of the ICRs of Peg3 and H19-imprinted domains were analyzed using the genomic sequences… read more here.
Keywords: h19 icr; peg3 h19; binding sites; tandem repeats ... See more keywords
Effects on gene expression and behavior of untagged short tandem repeats: the case of arginine vasopressin receptor 1a (AVPR1a) and externalizing behaviors
Sign Up to like & getrecommendations! Published in 2018 at "Translational Psychiatry"
DOI: 10.1038/s41398-018-0120-z
Abstract: Genome-wide association studies (GWAS) of complex, heritable, behavioral phenotypes have yielded an incomplete accounting of the genetic influences. The identified loci explain only a portion of the observed heritability, and few of the loci have… read more here.
Keywords: short tandem; receptor avpr1a; tandem repeats; arginine vasopressin ... See more keywords
Limpid hydrogels from β-turn motif-connected tandem repeats of Aβ16-22.
Sign Up to like & getrecommendations! Published in 2019 at "Soft matter"
DOI: 10.1039/c9sm00343f
Abstract: Self-assembling peptides constitute an important class of functional biomaterials. A number of short amyloidogenic stretches have been identified from amyloid proteins. Such peptides, as such or through subtle modifications, can turn out to be promising… read more here.
Keywords: turn motif; hydrogels turn; motif connected; limpid hydrogels ... See more keywords
Dinucleotide (CA)n tandem repeats on the human X-chromosome and the history of the Mediterranean populations
Sign Up to like & getrecommendations! Published in 2018 at "Annals of Human Biology"
DOI: 10.1080/03014460.2017.1414877
Abstract: Abstract Background: Tandem repeats (STRs) are genomic markers of particular interest in forensic and population genetics. Most of the population data currently available correspond to the variation of STRs of forensic panels, which barely include… read more here.
Keywords: dinucleotide tandem; genetics; strs; tandem repeats ... See more keywords
Decomposing mosaic tandem repeats accurately from long reads
Sign Up to like & getrecommendations! Published in 2023 at "Bioinformatics"
DOI: 10.1093/bioinformatics/btad185
Abstract: Abstract Motivation Over the past 30 years, extended tandem repeats (TRs) have been correlated with ∼60 diseases with high odds ratios, and most known TRs consist of single repeat units. However, in the last few years,… read more here.
Keywords: mosaic trs; repeats accurately; tandem repeats; accurately long ... See more keywords
Dot2dot: accurate whole-genome tandem repeats discovery
Sign Up to like & getrecommendations! Published in 2019 at "Bioinformatics"
DOI: 10.1093/bioinformatics/bty747
Abstract: Motivation Large‐scale sequencing projects have confirmed the hypothesis that eukaryotic DNA is rich in repetitions whose functional role needs to be elucidated. In particular, tandem repeats (TRs) (i.e. short, almost identical sequences that lie adjacent… read more here.
Keywords: dot2dot accurate; accurate whole; tandem repeats; whole genome ... See more keywords