Recognition of Dimethylarginine Analogues by Tandem Tudor Domain Protein Spindlin1
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DOI: 10.3390/molecules27030983
Abstract: Epigenetic readout of the combinatorial posttranslational modification comprised of trimethyllysine and asymmetric dimethylarginine (H3K4me3R8me2a) takes place via biomolecular recognition of tandem Tudor-domain-containing protein Spindlin1. Through comparative thermodynamic data and molecular dynamics simulations, we sought to… read more here.
Keywords: recognition; protein spindlin1; dimethylarginine; tandem tudor ... See more keywords