Phosphorylation-coupled autoregulation of TANGO1 and Sec16A maintains functional ER exit sites
Sign Up to like & getrecommendations! Published in 2025 at "Nature Communications"
DOI: 10.1038/s41467-025-65409-4
Abstract: Secretory proteins are synthesized in the endoplasmic reticulum (ER) and begin their transport from specialized domains on the ER called ER exit sites (ERES), where COPII proteins assemble. We previously demonstrated that the interaction between… read more here.
Keywords: phosphorylation; tango1 sec16a; exit sites; tango1 ... See more keywords
TANGO1 membrane helices create a lipid diffusion barrier at curved membranes
Sign Up to like & getrecommendations! Published in 2020 at "eLife"
DOI: 10.7554/elife.57822
Abstract: We have previously shown TANGO1 organises membranes at the interface of the endoplasmic reticulum (ER) and ERGIC/Golgi (Raote et al., 2018). TANGO1 corrals retrograde membranes at ER exit sites to create an export conduit. Here… read more here.
Keywords: helices create; tango1; membrane; create lipid ... See more keywords