Hydrolyzable Tannins Are Iron Chelators That Inhibit DNA Repair Enzyme ALKBH2.
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DOI: 10.1021/acs.chemrestox.8b00398
Abstract: Hydrolyzable tannins are a class of polyphenolic compounds commonly found in natural products. In this work, we studied the in vitro inhibitory mechanism of six molecules in this class on ALKBH2, an Fe(II)/α-ketoglutarate-dependent DNA repair… read more here.
Keywords: dna repair; repair enzyme; alkbh2; tannins iron ... See more keywords