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Published in 2021 at "Frontiers in Cellular Neuroscience"
DOI: 10.3389/fncel.2021.636017
Abstract: Rho-associated coiled-coil containing kinase isoform 2 (ROCK2) is a member of the AGC family of serine/threonine kinases and an extensively studied regulator of actin-mediated cytoskeleton contractility. Over the past decade, new evidence has emerged that…
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Keywords:
rock2 therapeutic;
perspectives rock2;
alzheimer disease;
disease ... See more keywords
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Published in 2022 at "Life"
DOI: 10.3390/life12091440
Abstract: Alzheimer’s disease (AD) is a heterogeneous neurodegenerative disorder and is the most common cause of dementia. Furthermore, aging is considered the most critical risk factor for AD. However, despite the vast amount of research and…
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Keywords:
therapeutic target;
disease;
alzheimer disease;
system therapeutic ... See more keywords
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Published in 2023 at "Pharmaceuticals"
DOI: 10.3390/ph16040580
Abstract: Alzheimer’s disease (AD) is the most common form of dementia. It increases the risk of other serious diseases and causes a huge impact on individuals, families, and socioeconomics. AD is a complex multifactorial disease, and…
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Keywords:
derived molecules;
enzyme inhibitors;
target alzheimer;
inhibitors target ... See more keywords