AMBRA1 and its role as a target for anticancer therapy
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Oncology"
DOI: 10.3389/fonc.2022.946086
Abstract: The activating molecule in Beclin1-regulated autophagy protein 1 (AMBRA1) is an intrinsically disordered protein that regulates the survival and death of cancer cells by modulating autophagy. Although the roles of autophagy in cancer are controversial… read more here.
Keywords: target anticancer; ambra1 role; therapy ambra1; therapy ... See more keywords
MicroRNA as an Important Target for Anticancer Drug Development
Sign Up to like & getrecommendations! Published in 2021 at "Frontiers in Pharmacology"
DOI: 10.3389/fphar.2021.736323
Abstract: Cancer has become the second greatest cause of death worldwide. Although there are several different classes of anticancer drugs that are available in clinic, some tough issues like side-effects and low efficacy still need to… read more here.
Keywords: drug development; mirna; anticancer drug; target anticancer ... See more keywords
Lysosomes as a Target of Anticancer Therapy
Sign Up to like & getrecommendations! Published in 2023 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms24032176
Abstract: Lysosomes are organelles containing acidic hydrolases that are responsible for lysosomal degradation and the maintenance of cellular homeostasis. They play an important role in autophagy, as well as in various cell death pathways, such as… read more here.
Keywords: target anticancer; cancer; lysosomes target; therapy ... See more keywords
Risk of serious adverse event and fatal adverse event with molecular target anticancer drugs in cancer patients: A meta-analysis
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Cancer Research and Therapeutics"
DOI: 10.4103/jcrt.jcrt_577_18
Abstract: Molecular target anticancer drugs are commonly used in various forms of cancers. It is a concern that the risk of serious adverse events (SAEs) and fatal adverse events (FAEs) of molecular target drugs are increasing.… read more here.
Keywords: molecular target; target anticancer; saes faes; target ... See more keywords