Articles with "target brca1" as a keyword



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Exploiting synthetic lethality to target BRCA1/2-deficient tumors: where we stand

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Published in 2021 at "Oncogene"

DOI: 10.1038/s41388-021-01744-2

Abstract: The principle of synthetic lethality, which refers to the loss of viability resulting from the disruption of two genes, which, individually, do not cause lethality, has become an attractive target approach due to the development… read more here.

Keywords: synthetic lethality; exploiting synthetic; lethality target; target brca1 ... See more keywords