circRNA is a potential target for cardiovascular diseases treatment.
Sign Up to like & getrecommendations! Published in 2021 at "Molecular and cellular biochemistry"
DOI: 10.1007/s11010-021-04286-z
Abstract: Circular RNAs (circRNAs), a novel class of endogenous noncoding RNA, are characterized by their covalently closed-loop structures without a 5' cap or a 3' poly(A) tail. With the evolution of high-throughput sequencing technology and bioinformatics,… read more here.
Keywords: potential target; biochemistry; target cardiovascular; cardiovascular diseases ... See more keywords
Triglycerides as target of cardiovascular risk reduction.
Sign Up to like & getrecommendations! Published in 2021 at "Current Opinion in Lipidology"
DOI: 10.1097/mol.0000000000000724
Abstract: DOI:10.1097/MOL.0000000000000724 Remnant lipoproteins represent an emerging risk factor not only for atherosclerotic cardiovascular disease (ASCVD) but also all-cause mortality [1 & ,2]. They are generated by incomplete lipoprotein lipase (LPL)-mediated hydrolysis of triglycerides within intestine-derived… read more here.
Keywords: triglycerides target; risk reduction; risk; cardiovascular risk ... See more keywords
CaMKII as a Therapeutic Target in Cardiovascular Disease.
Sign Up to like & getrecommendations! Published in 2022 at "Annual review of pharmacology and toxicology"
DOI: 10.1146/annurev-pharmtox-051421-111814
Abstract: CaMKII (the multifunctional Ca2+ and calmodulin-dependent protein kinase II) is a highly validated signal for promoting a variety of common diseases, particularly in the cardiovascular system. Despite substantial amounts of convincing preclinical data, CaMKII inhibitors… read more here.
Keywords: camkii therapeutic; therapeutic target; toxicology; pharmacology ... See more keywords