Two HEPN domains dictate CRISPR RNA maturation and target cleavage in Cas13d
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DOI: 10.1038/s41467-019-10507-3
Abstract: Cas13d, the type VI-D CRISPR-Cas effector, is an RNA-guided ribonuclease that has been repurposed to edit RNA in a programmable manner. Here we report the detailed structural and functional analysis of the uncultured Ruminococcus sp.… read more here.
Keywords: rna; crrna; cas13d; target cleavage ... See more keywords