Articles with "target colon" as a keyword



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KRAS: A Druggable Target in Colon Cancer Patients

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Published in 2022 at "International Journal of Molecular Sciences"

DOI: 10.3390/ijms23084120

Abstract: Mutations in KRAS are among the most frequent aberrations in cancer, including colon cancer. KRAS direct targeting is daunting due to KRAS protein resistance to small molecule inhibition. Moreover, its elevated affinity to cellular guanosine… read more here.

Keywords: target colon; druggable target; kras druggable; cancer ... See more keywords
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Carboxymethyl Tamarind Seed Kernel Polysaccharide Formulated into Pellets to Target at Colon

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Published in 2018 at "Indian Journal of Pharmaceutical Education and Research"

DOI: 10.5530/ijper.52.3.42

Abstract: Objective: Tamarind seed polysaccharide (TSP) modifying to carboxymethyl tamarind seed kernel polysaccharide (CMTSP) could be potential polymer over synthetic one to target colon diseases. Ibuprofen was loaded in CMTSP to achieve colon targeted sustained action… read more here.

Keywords: target colon; seed; carboxymethyl tamarind; seed kernel ... See more keywords