miR-124, a potential therapeutic target in colorectal cancer
Sign Up to like & getrecommendations! Published in 2019 at "OncoTargets and therapy"
DOI: 10.2147/ott.s179501
Abstract: Recently, miR-124 has been regarded as a critical modulator of colorectal cancer. We here summarize the studies on the role and mechanism of miR-124 in colorectal cancer. They indicate that miR-124 is methylated during carcinogenesis… read more here.
Keywords: target colorectal; colorectal cancer; therapeutic target; mir 124 ... See more keywords
Novel Set of Diarylmethanes to Target Colorectal Cancer: Synthesis, In Vitro and In Silico Studies
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DOI: 10.3390/biom13010054
Abstract: Distinctive structural, chemical, and physical properties make the diarylmethane scaffold an essential constituent of many active biomolecules nowadays used in pharmaceutical, agrochemical, and material sciences. In this work, 33 novel diarylmethane molecules aiming to target… read more here.
Keywords: set diarylmethanes; synthesis; novel set; colorectal cancer ... See more keywords
TOMM20 as a potential therapeutic target of colorectal cancer
Sign Up to like & getrecommendations! Published in 2019 at "BMB Reports"
DOI: 10.5483/bmbrep.2019.52.12.249
Abstract: Translocase of outer mitochondrial membrane 20 (TOMM20) plays an essential role as a receptor for proteins targeted to mitochondria. TOMM20 was shown to be overexpressed in various cancers. However, the oncological function and therapeutic potential… read more here.
Keywords: therapeutic target; cancer; tomm20; target colorectal ... See more keywords