Translational Models to Predict Target Concentrations for Pre-Exposure Prophylaxis in Women.
Sign Up to like & getrecommendations! Published in 2022 at "AIDS research and human retroviruses"
DOI: 10.1089/aid.2022.0057
Abstract: The HIV epidemic remains a significant public health burden. Women represent half of the global HIV epidemic, yet there is an urgent need for a variety of prevention options to meet the needs of more… read more here.
Keywords: hiv; exposure prophylaxis; target concentrations; pre exposure ... See more keywords
Experience of a Strategy Including CYP2C19 Preemptive Genotyping Followed by Therapeutic Drug Monitoring of Voriconazole in Patients Undergoing Allogenic Hematopoietic Stem Cell Transplantation
Sign Up to like & getrecommendations! Published in 2021 at "Frontiers in Pharmacology"
DOI: 10.3389/fphar.2021.717932
Abstract: Many factors have been described to contribute to voriconazole (VCZ) interpatient variability in plasma concentrations, especially CYP2C19 genetic variability. In 2014, Hicks et al. presented data describing the correlation between VCZ plasma concentrations and CYP2C19… read more here.
Keywords: initial dose; target concentrations; preemptive genotyping; vcz ... See more keywords