Progranulin as a therapeutic target for dementia
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DOI: 10.1080/14728222.2018.1487951
Abstract: ABSTRACT Introduction: Progranulin (PGRN) is an acrosomal glycoprotein that is synthesized during spermatogenesis. It is overexpressed in tumors and has anti-inflammatory properties. The protein may be cleaved into granulins which display pro-inflammatory properties. In 2006,… read more here.
Keywords: progranulin therapeutic; target dementia; therapeutic target; pgrn ... See more keywords