Off-target Editing by CRISPR-guided DNA base editors.
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DOI: 10.1021/acs.biochem.9b00573
Abstract: Base editing is a genome editing strategy that induces specific single nucleotide changes within genomic DNA. Two major DNA base editors, Cytosine base editors (CBEs) and Adenine base editors (ABEs), have been developed that consist… read more here.
Keywords: crispr; base editors; target editing; dna base ... See more keywords