Multi‐target Fragments Display Versatile Binding Modes
Sign Up to like & getrecommendations! Published in 2017 at "Molecular Informatics"
DOI: 10.1002/minf.201700042
Abstract: Promiscuity is an interesting concept in fragment‐based drug design as fragments with low specificity can be advantageous for finding many screening hits. We present a PDB‐wide analysis of multi‐target fragments and their binding mode conservation.… read more here.
Keywords: fragments display; target fragments; binding modes; display versatile ... See more keywords
Dose build-up effects induced by delta electrons and target fragments in proton Bragg curves-measurements and simulations.
Sign Up to like & getrecommendations! Published in 2018 at "Physics in medicine and biology"
DOI: 10.1088/1361-6560/aad8fc
Abstract: Dose build-up effects in the entrance channel of proton Bragg curves were investigated in detail by means of simulations and experiments. There are two relevant dose build-up effects. Firstly, the δ-electron build-up effect which takes… read more here.
Keywords: proton bragg; target fragments; target; build effects ... See more keywords