Identification of hsa‐mir‐34a, hsa‐mir‐124, and hsa‐mir‐204 as signatures for cataract
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Cellular Physiology"
DOI: 10.1002/jcp.27741
Abstract: Cataract, one of the common age‐related diseases that remains the leading cause of blindness worldwide. There have been studies pertaining to microRNA (miRNA) effects on cataract pathogenesis. However, the results were different from each other… read more here.
Keywords: target genes; hsa mir; mir 34a; hsa ... See more keywords
Analysis of the Teashirt Target Genes in Ureteric Bud Development.
Sign Up to like & getrecommendations! Published in 2019 at "Methods in molecular biology"
DOI: 10.1007/978-1-4939-9021-4_18
Abstract: Microarrays and RNA-seq (RNA sequencing) are powerful techniques to assess transcript abundance in biological samples and to improve our understanding of the relationship between genotype and phenotype. Tshz3+/- heterozygous mouse is a model for a… read more here.
Keywords: bud development; target genes; genes ureteric; ureteric bud ... See more keywords
RNAi for management of Asian long-horned beetle, Anoplophora glabripennis: identification of target genes
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Pest Science"
DOI: 10.1007/s10340-020-01197-8
Abstract: The Asian long-horned beetle (ALB), Anoplophora glabripennis, is a serious invasive forest pest in several countries, including the USA. Currently, there are no effective methods available to manage this pest without adverse impacts on the… read more here.
Keywords: target genes; horned beetle; anoplophora glabripennis; target ... See more keywords
Single-Nucleotide Variants in microRNAs Sequences or in their Target Genes Might Influence the Risk of Epilepsy: A Review.
Sign Up to like & getrecommendations! Published in 2021 at "Cellular and molecular neurobiology"
DOI: 10.1007/s10571-021-01058-7
Abstract: Single-nucleotide variant (SNV) is a single base mutation at a specific location in the genome and may play an import role in epilepsy pathophysiology. The aim of this study was to review case-control studies that… read more here.
Keywords: epilepsy; sequences target; target genes; single nucleotide ... See more keywords
Identification and characterization of drought responsive microRNAs and their target genes in cardamom (Elettaria cardamomum Maton)
Sign Up to like & getrecommendations! Published in 2018 at "Plant Growth Regulation"
DOI: 10.1007/s10725-018-0462-9
Abstract: Plant miRNAs are found to be present throughout the genome and they regulate gene expression either by cleaving mRNA or inhibiting the translational process at the post transcriptional level. Drought is one of the major… read more here.
Keywords: target genes; target; drought responsive; stress ... See more keywords
MicroRNA expression, target genes, and signaling pathways in infants with a ventricular septal defect
Sign Up to like & getrecommendations! Published in 2017 at "Molecular and Cellular Biochemistry"
DOI: 10.1007/s11010-017-3146-2
Abstract: This study aimed to systematically investigate the relationship between miRNA expression and the occurrence of ventricular septal defect (VSD), and characterize the miRNA target genes and pathways that can lead to VSD. The miRNAs that… read more here.
Keywords: signaling pathways; target genes; ventricular septal; septal defect ... See more keywords
Identification of novel miRNAs and their target genes from Populus szechuanica infected with Melampsora larici-populina
Sign Up to like & getrecommendations! Published in 2019 at "Molecular Biology Reports"
DOI: 10.1007/s11033-019-04746-2
Abstract: Two novel miRNAs were selected from a pre-constructed RNA library of Populus szechuanica infected with the foliar rust fungus Melampsora larici-populina in order to detect the genes regulated as targets of the miRNAs novel_mir_11 and… read more here.
Keywords: target genes; mirnas target; szechuanica infected; populus szechuanica ... See more keywords
Identification of Rfx6 target genes involved in pancreas development and insulin translation by ChIP-seq.
Sign Up to like & getrecommendations! Published in 2019 at "Biochemical and biophysical research communications"
DOI: 10.1016/j.bbrc.2018.11.133
Abstract: Regulatory Factor X-box binding transcriptional factor 6 (Rfx6) plays an important role in the differentiation and development of pancreas in mammals. However, the direct target genes of Rfx6 to regulate this process were largely unknown.… read more here.
Keywords: chip seq; target genes; target; insulin translation ... See more keywords
Linker Histone H1.2 Directs Genome-wide Chromatin Association of the Retinoblastoma Tumor Suppressor Protein and Facilitates Its Function
Sign Up to like & getrecommendations! Published in 2017 at "Cell Reports"
DOI: 10.1016/j.celrep.2017.05.053
Abstract: Summary The retinoblastoma tumor suppressor protein pRb is a master regulator of cellular proliferation, principally through interaction with E2F and regulation of E2F target genes. Here, we describe the H1.2 linker histone as a major… read more here.
Keywords: target genes; tumor suppressor; prb; suppressor protein ... See more keywords
miR-424 induces apoptosis in glioblastoma cells and targets AKT1 and RAF1 oncogenes from the ERBB signaling pathway.
Sign Up to like & getrecommendations! Published in 2021 at "European journal of pharmacology"
DOI: 10.1016/j.ejphar.2021.174273
Abstract: Glioblastoma is a lethal and incurable cancer. Tumor suppressor miRNAs are promising gene therapy tools for cancer treatment. In silico, we predicted miR-424 as a tumor suppressor. It had several target genes from the epidermal… read more here.
Keywords: mir 424; target genes; glioblastoma; tumor suppressor ... See more keywords
Pharmacological mechanism of Astragalus and Angelica in the treatment of idiopathic pulmonary fibrosis based on network pharmacology
Sign Up to like & getrecommendations! Published in 2019 at "European Journal of Integrative Medicine"
DOI: 10.1016/j.eujim.2019.101003
Abstract: Abstract Introduction Herbal medicine is varied and complex, and research on multi-component, multi-target and multi-pathways of Astragalus and Angelica is lacking. This study aimed to study the pharmacological mechanism of Astragalus and Angelica in the… read more here.
Keywords: medicine; target genes; astragalus angelica; angelica treatment ... See more keywords