Dual-target kinase drug design: Current strategies and future directions in cancer therapy.
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DOI: 10.1016/j.ejmech.2019.112025
Abstract: Protein kinases are well-known to orchestrate the activation of signaling cascades in response to extracellular and intracellular stimuli to control cell proliferation and survival. The perturbation of such kinases by some mutation or abnormal protein… read more here.
Keywords: dual target; target kinase; chemistry; drug ... See more keywords