Articles with "target osteosarcoma" as a keyword



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Identification of Gαi3 as a promising target for osteosarcoma treatment

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Published in 2022 at "International Journal of Biological Sciences"

DOI: 10.7150/ijbs.68861

Abstract: Sustained activation of multiple receptor tyrosine kinases (RTKs) simultaneously is vital for tumorigenesis and progression of osteosarcoma (OS). Gαi proteins recruitment to various RTKs mediates downstream oncogenic signaling activation. The expression, functions and underlying mechanisms… read more here.

Keywords: identification promising; target osteosarcoma; promising target; primary cells ... See more keywords