Strategies to Reduce the On‐Target Platelet Toxicity of Bcl‐xL Inhibitors: PROTACs, SNIPERs and Prodrug‐Based Approaches
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DOI: 10.1002/cbic.202100689
Abstract: Apoptosis is a highly regulated cellular process. Aberration in apoptosis is a common characteristic of various disorders. Therefore, proteins involved in apoptosis are prime targets in multiple therapies. Bcl‐xL is an antiapoptotic protein. Compared to… read more here.
Keywords: pharmacology; based approaches; bcl; target platelet ... See more keywords