Paradox-Breaking RAF Inhibitors that Also Target SRC Are Effective in Drug-Resistant BRAF Mutant Melanoma
Sign Up to like & getrecommendations! Published in 2017 at "Cancer Cell"
DOI: 10.1016/j.ccell.2017.02.007
Abstract: Citation for published version: Girotti, MR, Lopes, F, Preece, N, Niculescu-Duvaz, D, Zambon, A, Davies, L, Whittaker, S, Saturno, G, Viros, A, Pedersen, M, Suijkerbuijk, BMJM, Menard, D, McLeary, R, Johnson, L, Fish, L, Ejiama,… read more here.
Keywords: also target; paradox breaking; raf inhibitors; breaking raf ... See more keywords
Occludin is a target of Src kinase and promotes lipid secretion by binding to BTN1a1 and XOR
Sign Up to like & getrecommendations! Published in 2022 at "PLoS Biology"
DOI: 10.1371/journal.pbio.3001518
Abstract: Lipid droplets (LDs) have increasingly been recognized as an essential organelle for eukaryotes. Although the biochemistry of lipid synthesis and degradation is well characterized, the regulation of LD dynamics, including its formation, maintenance, and secretion,… read more here.
Keywords: secretion; target src; btn1a1 xor; src kinase ... See more keywords