Telomerase: A Target for Therapeutic Effects of Curcumin in Cancer.
Sign Up to like & getrecommendations! Published in 2021 at "Advances in experimental medicine and biology"
DOI: 10.1007/978-3-030-55035-6_10
Abstract: Telomerases are attractive targets for development of new anticancer agents. Most tumors express the enzyme telomerase that maintains telomere length and thus ensures indefinite cell proliferation, a hallmark of cancer. Curcumin has been shown to… read more here.
Keywords: telomerase target; target therapeutic; telomerase; effects curcumin ... See more keywords
Adaptive iron utilization compensates for the lack of an inducible uptake system in Naegleria fowleri and represents a potential target for therapeutic intervention
Sign Up to like & getrecommendations! Published in 2020 at "PLoS Neglected Tropical Diseases"
DOI: 10.1371/journal.pntd.0007759
Abstract: Naegleria fowleri is a single-cell organism living in warm freshwater that can become a deadly human pathogen known as a brain-eating amoeba. The condition caused by N. fowleri, primary amoebic meningoencephalitis, is usually a fatal… read more here.
Keywords: potential target; target therapeutic; naegleria fowleri; therapeutic intervention ... See more keywords
Heme as a Target for Therapeutic Interventions
Sign Up to like & getrecommendations! Published in 2017 at "Frontiers in Pharmacology"
DOI: 10.3389/fphar.2017.00146
Abstract: Heme is a complex of iron and the tetrapyrrole protoporphyrin IX with essential functions in aerobic organisms. Heme is the prosthetic group of hemoproteins such as hemoglobin and myoglobin, which are crucial for reversible oxygen… read more here.
Keywords: heme; target therapeutic; heme target; therapeutic interventions ... See more keywords
Feasibility Analysis of Interleukin-13 as a Target for a Therapeutic Vaccine
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DOI: 10.3390/vaccines7010020
Abstract: Background: The development of therapeutic vaccines requires thorough knowledge of potential hazards associated with long-term inactivation of self-proteins. Among potential targets, interleukin 13 (IL-13) merits consideration, as monoclonal antibodies disrupting IL-13 signaling are proving to… read more here.
Keywords: target therapeutic; analysis interleukin; feasibility analysis; target ... See more keywords