A chronotherapeutics-applicable multi-target therapeutics based on AI: Example of therapeutic hypothermia
Sign Up to like & getrecommendations! Published in 2022 at "Briefings in Bioinformatics"
DOI: 10.1093/bib/bbac365
Abstract: Abstract Nowadays, the complexity of disease mechanisms and the inadequacy of single-target therapies in restoring the biological system have inevitably instigated the strategy of multi-target therapeutics with the analysis of each target individually. However, it… read more here.
Keywords: target therapeutics; therapeutic hypothermia; multi target; target ... See more keywords
Elabela peptide: an emerging target in therapeutics.
Sign Up to like & getrecommendations! Published in 2022 at "Current drug targets"
DOI: 10.2174/1389450123666220826160123
Abstract: Elabela, a bioactive micropeptide, is recognized as the second endogenous ligand for Apelin receptor and is widely distributed in different tissues and organs. Elabela plays important role in various physiological processes such blood pressure control,… read more here.
Keywords: emerging target; target therapeutics; peptide emerging; elabela peptide ... See more keywords
TLR10 and Its Unique Anti-Inflammatory Properties and Potential Use as a Target in Therapeutics
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DOI: 10.4110/in.2020.20.e21
Abstract: TLRs are pattern recognition receptors (PRRs) whose cytoplasmic signalling domain is similar to that of IL-1. The extracellular domain of TLRs serve as the binding site of pathogen associated molecular patterns. TLRs are found on… read more here.
Keywords: anti inflammatory; tlr10 unique; target therapeutics; inflammatory properties ... See more keywords