Abstract 4660: Molecular mechanisms by which a bioactivated human carcinogen is transported to target tissues
Sign Up to like & getrecommendations! Published in 2019 at "Tumor Biology"
DOI: 10.1158/1538-7445.am2019-4660
Abstract: Aristolochic acid (AA) is a potent human carcinogen and nephrotoxin found in preparations of Aristolochia plants used in Chinese Traditional Medicine. Following biotransformation to form N-sulfonyloxyaristolactam (AL-I-NOSO3), this intermediate undergoes heterolytic cleavage of the sulfate… read more here.
Keywords: transported target; human carcinogen; hsa; target tissues ... See more keywords
Gene Expression Signatures Reveal Common Virus Infection Pathways in Target Tissues of Type 1 Diabetes, Hashimoto’s Thyroiditis, and Celiac Disease
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DOI: 10.3389/fimmu.2022.891698
Abstract: Type 1 diabetes (T1D) patients are at heightened risk for other autoimmune disorders, particularly Hashimoto’s thyroiditis (HT) and celiac disease (CD). Recent evidence suggests that target tissues of autoimmune diseases engage in a harmful dialogue… read more here.
Keywords: celiac disease; hashimoto thyroiditis; target tissues; thyroiditis celiac ... See more keywords
Integrated or Independent Actions of Metformin in Target Tissues Underlying Its Current Use and New Possible Applications in the Endocrine and Metabolic Disorder Area
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DOI: 10.3390/ijms222313068
Abstract: Metformin is considered the first-choice drug for type 2 diabetes treatment. Actually, pleiotropic effects of metformin have been recognized, and there is evidence that this drug may have a favorable impact on health beyond its… read more here.
Keywords: actions metformin; target tissues; integrated independent; independent actions ... See more keywords