T cell receptor engineering of primary NK cells to therapeutically target tumors and tumor immune evasion
Sign Up to like & getrecommendations! Published in 2022 at "Journal for Immunotherapy of Cancer"
DOI: 10.1136/jitc-2021-003715
Abstract: Background T cell receptor (TCR)-engineered cells can be powerful tools in the treatment of malignancies. However, tumor resistance by Human Leukocyte antigen (HLA) class I downregulation can negatively impact the success of any TCR-mediated cell… read more here.
Keywords: target tumors; cell; tcr; primary cells ... See more keywords
Pacifastin-derived Peptides Target Tumors for Use in In Vivo Imaging.
Sign Up to like & getrecommendations! Published in 2018 at "Anticancer research"
DOI: 10.21873/anticanres.12191
Abstract: BACKGROUND/AIM Developments in imaging have improved cancer diagnosis, but identification of malignant cells during surgical resection remains a challenge. The aim of this study was to investigate the pacifastin family of peptides for novel activity… read more here.
Keywords: target tumors; tumors use; pacifastin derived; derived peptides ... See more keywords