Identifying the natural polyphenol catechin as a multi-targeted agent against SARS-CoV-2 for the plausible therapy of COVID-19: an integrated computational approach
Sign Up to like & getrecommendations! Published in 2021 at "Briefings in Bioinformatics"
DOI: 10.1093/bib/bbaa378
Abstract: Abstract The global pandemic crisis, coronavirus disease 2019 (COVID-19), caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has claimed the lives of millions of people across the world. Development and testing of anti-SARS-CoV-2… read more here.
Keywords: computational approach; targeted agent; covid; sars cov ... See more keywords
Canadian profiling and targeted agent utilization trial (CAPTUR/PM.1): A phase II basket precision medicine trial.
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Clinical Oncology"
DOI: 10.1200/jco.2018.36.15_suppl.tps12127
Abstract: TPS12127Background: Genomic profiling of cancers is increasingly used to refine prognostication and aid in treatment decisions by allowing matching of targeted agents to specific genetic variants. ... read more here.
Keywords: medicine; profiling targeted; trial; targeted agent ... See more keywords
Meta-analysis of gemcitabine plus nab-paclitaxel combined with targeted agents in the treatment of metastatic pancreatic cancer
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DOI: 10.12998/wjcc.v10.i27.9703
Abstract: BACKGROUND Gemcitabine plus nab-paclitaxel (GA) is a commonly used first-line treatment regimen for metastatic pancreatic cancer, and many studies will add a novel targeted agent to this regimen for improving patient survival rate. However, the… read more here.
Keywords: gemcitabine plus; targeted agent; metastatic pancreatic; pancreatic cancer ... See more keywords
Targeted and immune therapies for hepatocellular carcinoma: Predictions for 2019 and beyond
Sign Up to like & getrecommendations! Published in 2019 at "World Journal of Gastroenterology"
DOI: 10.3748/wjg.v25.i7.789
Abstract: Systemic therapy for hepatocellular carcinoma (HCC) has markedly advanced since the survival benefit of a molecular targeted agent, sorafenib, were demonstrated in the SHARP and Asia Pacific trials in 2007. Treatment options for patients with… read more here.
Keywords: hepatocellular carcinoma; line; targeted agent; molecular targeted ... See more keywords