Targeted Bmal1 restoration in muscle prolongs lifespan with systemic health effects in aging model
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DOI: 10.1172/jci.insight.174007
Abstract: Disruption of the circadian clock in skeletal muscle worsens local and systemic health, leading to decreased muscle strength, metabolic dysfunction, and aging-like phenotypes. Whole-body knockout mice that lack Bmal1, a key component of the molecular… read more here.
Keywords: skeletal muscle; muscle; targeted bmal1; systemic health ... See more keywords