Untargeted CUT&Tag reads are enriched at accessible chromatin and restrict identification of potential G4-forming sequences in G4-targeted CUT&Tag experiments
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DOI: 10.1093/nar/gkaf678
Abstract: Abstract G-quadruplex DNA structures (G4s) form within single-stranded DNA in nucleosome-free chromatin. G4s modulate gene expression and genomic stability, so high-throughput, genome-wide mapping of G4s has generated strong research interest and methodological innovation. Recently, the… read more here.
Keywords: targeted cut; cut tag; g4s; untargeted cut ... See more keywords