Modular Metal-Organic Polyhedra Superassembly: From Molecular-Level Design to Targeted Drug Delivery.
Sign Up to like & getrecommendations! Published in 2019 at "Advanced materials"
DOI: 10.1002/adma.201806774
Abstract: Targeted drug delivery remains at the forefront of biomedical research but remains a challenge to date. Herein, the first superassembly of nanosized metal-organic polyhedra (MOP) and their biomimetic coatings of lipid bilayers are described to… read more here.
Keywords: organic polyhedra; drug delivery; delivery; metal organic ... See more keywords
Targeted Drug Delivery to Stroke via Chemotactic Recruitment of Nanoparticles Coated with Membrane of Engineered Neural Stem Cells.
Sign Up to like & getrecommendations! Published in 2019 at "Small"
DOI: 10.1002/smll.201902011
Abstract: Cell membrane coating has recently emerged as a promising biomimetic approach to engineering nanoparticles (NPs) for targeted drug delivery. However, simple cell membrane coating may not meet the need for efficient drug delivery to the… read more here.
Keywords: drug delivery; delivery; targeted drug; membrane ... See more keywords
Artificial Glycoproteins as a Scaffold for Targeted Drug Therapy.
Sign Up to like & getrecommendations! Published in 2020 at "Small"
DOI: 10.1002/smll.201906890
Abstract: Akin to a cellular "fingerprint," the glycocalyx is a glycan-enriched cellular coating that plays a crucial role in mediating cell-to-cell interactions. To gain a better understanding of the factors that govern in vivo recognition, artificial… read more here.
Keywords: artificial glycoproteins; drug therapy; drug; targeted drug ... See more keywords
Preparation of a tumor-targeted drug-loading material, amphiphilic peptide P10, and analysis of its anti-tumor activity
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Materials Science: Materials in Medicine"
DOI: 10.1007/s10856-018-6204-8
Abstract: AbstractA new tumor-targeted drug-loading material, the amphiphilic peptide DGRGGGAAAA (P10) was designed and synthesized, and its self-assembly behavior, drug-loading effects and in vitro characteristics were studied. P10 was synthesized by solid-state synthesis and doxorubicin (DOX)… read more here.
Keywords: drug loading; drug; targeted drug; p10 ... See more keywords
Magnetic Nanoparticles in Targeted Drug Delivery: a Review
Sign Up to like & getrecommendations! Published in 2021 at "Journal of Superconductivity and Novel Magnetism"
DOI: 10.1007/s10948-021-05932-9
Abstract: Magnetic nanoparticles are one of the most important and widely used types of nanomaterials, whose unique properties make them special compared to other nanostructures. These particles can be used in various fields. But their role… read more here.
Keywords: nanoparticles targeted; drug delivery; magnetic nanoparticles; drug ... See more keywords
Dual pH-/thermo-responsive chitosan-based hydrogels prepared using "click" chemistry for colon-targeted drug delivery applications.
Sign Up to like & getrecommendations! Published in 2021 at "Carbohydrate polymers"
DOI: 10.1016/j.carbpol.2021.117812
Abstract: A dual pH-/thermo-responsive hydrogel was designed based on a polyelectrolyte complex of polyacrylic acid (PAA) and norbornene-functionalized chitosan (CsNb), which was synergized with chemical crosslinking using bistetrazine-poly(N-isopropyl acrylamide) (bisTz-PNIPAM). The thermo-responsive polymeric crosslinker, bisTz-PNIPAM, was… read more here.
Keywords: thermo responsive; chemistry; colon targeted; dual thermo ... See more keywords
Advances in glycosylation-mediated cancer-targeted drug delivery.
Sign Up to like & getrecommendations! Published in 2018 at "Drug discovery today"
DOI: 10.1016/j.drudis.2018.02.009
Abstract: Targeted drug delivery for cancer therapy is expected to enhance therapeutic efficacy with minimized side effects, where the ligand-receptor recognition serves as a common targeting approach. Various ligands have been reported and carbohydrates, one of… read more here.
Keywords: drug delivery; glycosylation mediated; drug; targeted drug ... See more keywords
Synthesis of pH-sensitive nanocarriers based on polyacrylamide grafted nanocrystalline cellulose for targeted drug delivery to folate receptor in breast cancer cells
Sign Up to like & getrecommendations! Published in 2021 at "European Polymer Journal"
DOI: 10.1016/j.eurpolymj.2021.110398
Abstract: Abstract In this study, nanocrystalline cellulose (NCC) was prepared for the synthesis of new nanocarriers from microcrystalline cellulose to the targeted drug delivery of doxorubicin (DOX) and then a chlorinated derivative of the NCC was… read more here.
Keywords: cellulose targeted; nanocrystalline cellulose; drug; breast cancer ... See more keywords
Albumin nanoparticles conjugates binding with glycan - A strategic approach for targeted drug delivery.
Sign Up to like & getrecommendations! Published in 2019 at "International journal of biological macromolecules"
DOI: 10.1016/j.ijbiomac.2018.12.184
Abstract: Understanding the transcytosis phenomenon through albumin binding receptor (glycoproteins) is an important step towards targeted drug delivery research. The transcytosis of bovine serum albumin (BSA) occurs through its uptake by binding to glycoprotein (gp60) present… read more here.
Keywords: drug delivery; bsa; targeted drug; spectroscopy ... See more keywords
A novel peptide ligand RAP12 of LRP1 for glioma targeted drug delivery
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Controlled Release"
DOI: 10.1016/j.jconrel.2018.04.035
Abstract: ABSTRACT The receptor associated protein (RAP) is a 39kDa chaperone protein, binding tightly to low‐density lipoprotein receptor‐related protein‐1 (LRP1) that is overexpressed in glioma, tumor neovasculature, vasculogenic mimicry (VM), the blood–brain barrier (BBB) and the… read more here.
Keywords: glioma; rap12 lrp1; drug delivery; glioma targeted ... See more keywords
Bovine serum albumin conjugation on poly(methyl methacrylate) nanoparticles for targeted drug delivery applications
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Drug Delivery Science and Technology"
DOI: 10.1016/j.jddst.2019.101490
Abstract: Abstract During the application of nanoparticles (NPs) in vivo, it is inevitable that the adsorption of proteins takes place on the surface of the nanocarriers. The formation of this protein corona determines the “identity” of… read more here.
Keywords: drug delivery; drug; poly methyl; targeted drug ... See more keywords