Epigenetic editing: How cutting-edge targeted epigenetic modification might provide novel avenues for autoimmune disease therapy.
Sign Up to like & getrecommendations! Published in 2018 at "Clinical immunology"
DOI: 10.1016/j.clim.2018.02.001
Abstract: Autoimmune diseases are enigmatic and complex, and most been associated with epigenetic changes. Epigenetics describes changes in gene expression related to environmental influences mediated by a variety of effectors that alter the three-dimensional structure of… read more here.
Keywords: edge targeted; cutting edge; targeted epigenetic; autoimmune disease ... See more keywords
New targeted and epigenetic therapeutic strategies for the treatment of uveal melanoma.
Sign Up to like & getrecommendations! Published in 2022 at "Cancer gene therapy"
DOI: 10.1038/s41417-022-00443-8
Abstract: Uveal melanoma (UM) is a rare, genetically bland ocular malignancy with excellent local treatment options, but no disease-specific therapies are approved for use in the metastatic setting by the Food and Drug Administration. Metastatic UM… read more here.
Keywords: uveal melanoma; epigenetic therapeutic; new targeted; therapeutic strategies ... See more keywords
Abstract 6085: Leveraging targeted epigenetic and genetic detection for cost-effective cancer classification
Sign Up to like & getrecommendations! Published in 2024 at "Cancer Research"
DOI: 10.1158/1538-7445.am2024-6085
Abstract: The combinatorial power of genetics and epigenetics is vital to understanding biology in healthy and cancerous states. Utilizing a recent novel approach, we enable the simultaneous identification of modified cytosine and the canonical bases A,… read more here.
Keywords: detection; cancer; leveraging targeted; targeted epigenetic ... See more keywords
Methylation modification in gastric cancer and approaches to targeted epigenetic therapy (Review).
Sign Up to like & getrecommendations! Published in 2017 at "International journal of oncology"
DOI: 10.3892/ijo.2017.3981
Abstract: Gastric cancer (GC) is one of the most common cancers and the second leading cause of cancer-related mortality. Increasing discoveries have highlighted aberrant epigetic modifications actively contribute to the pathogenesis of this fatal disease. Among… read more here.
Keywords: methylation; gastric cancer; epigenetic therapy; targeted epigenetic ... See more keywords