Design and Application of Receptor-Targeted Fluorescent Probes Based on Small Molecular Fluorescent Dyes.
Sign Up to like & getrecommendations! Published in 2021 at "Bioconjugate chemistry"
DOI: 10.1021/acs.bioconjchem.0c00606
Abstract: In recent years, a variety of receptor-targeted fluorescent probes have been developed and widely used to realize the visualization of certain receptors, which facilitates the early diagnosis and treatment of diseases. In this Review, we… read more here.
Keywords: targeted fluorescent; application receptor; receptor targeted; fluorescent probes ... See more keywords
A mitochondria-targeted fluorescent probe for monitoring endogenous cysteine in living cells and zebrafish.
Sign Up to like & getrecommendations! Published in 2021 at "Chemical communications"
DOI: 10.1039/d1cc03307g
Abstract: At the organelle level, pathogenesis due to abnormal concentrations of cysteine (Cys) is of great significance for the early diagnosis and treatment of related diseases. Generally speaking, organelle localization requires the participation of specific target… read more here.
Keywords: mitochondria targeted; fluorescent probe; probe; cells zebrafish ... See more keywords
Mitochondria-targeted fluorescent probe for visualization of exogenous and endogenous methylglyoxal in living cells.
Sign Up to like & getrecommendations! Published in 2022 at "Chemical communications"
DOI: 10.1039/d2cc01503j
Abstract: An activatable mitochondria-targeted fluorescent probe Hcy-OPD was synthesized for the detection of methylglyoxal (MGO). For the introduction of a preorganized isopropylamino group on the aromatic o-diamine framework to regulate the hindrance effect, Hcy-OPD showed high… read more here.
Keywords: targeted fluorescent; mitochondria targeted; living cells; exogenous endogenous ... See more keywords
Convolution Neural Networks and Targeted Fluorescent Nanoparticles to Detect and ICDAS Score Caries
Sign Up to like & getrecommendations! Published in 2022 at "Caries Research"
DOI: 10.1159/000527118
Abstract: Previous work has shown targeted fluorescent starch nanoparticles (TFSNs) can label the subsurface of carious lesions and assist dental professionals in the diagnostic process. In this study, we aimed to evaluate the potential of using… read more here.
Keywords: carious lesions; neural networks; convolution neural; targeted fluorescent ... See more keywords
Mitochondrial targeted fluorescent nitrite peroxide probe for dynamic monitoring of cellular lung injury.
Sign Up to like & getrecommendations! Published in 2023 at "Analytical biochemistry"
DOI: 10.2139/ssrn.4135991
Abstract: Herein, a mitochondrial targeted fluorescent nitrite peroxide probe CHP for dynamic monitoring of cellular lung injury was developed. For the practical delivery and selectivity, the structural features including pyridine head and borate recognition group were… read more here.
Keywords: targeted fluorescent; cellular lung; mitochondrial targeted; lung injury ... See more keywords
Organelle-Targeted Fluorescent Probes for Sulfane Sulfur Species
Sign Up to like & getrecommendations! Published in 2023 at "Antioxidants"
DOI: 10.3390/antiox12030590
Abstract: Sulfane sulfurs, which include hydropersulfides (RSSH), hydrogen polysulfides (H2Sn, n > 1), and polysulfides (RSnR, n > 2), play important roles in cellular redox biology and are closely linked to hydrogen sulfide (H2S) signaling. While… read more here.
Keywords: sulfane sulfur; sulfur species; targeted fluorescent; organelle targeted ... See more keywords
Tumor-Targeted Fluorescent Proteinoid Nanocapsules Encapsulating Synergistic Drugs for Personalized Cancer Therapy
Sign Up to like & getrecommendations! Published in 2021 at "Pharmaceuticals"
DOI: 10.3390/ph14070648
Abstract: Personalized cancer treatment based on specific mutations offers targeted therapy and is preferred over “standard” chemotherapy. Proteinoid polymers produced by thermal step-growth polymerization of amino acids may form nanocapsules (NCs) that encapsulate drugs overcoming miscibility… read more here.
Keywords: therapy; targeted fluorescent; personalized cancer; cancer ... See more keywords
Rational Design of Organelle-Targeted Fluorescent Probes: Insights from Artificial Intelligence
Sign Up to like & getrecommendations! Published in 2023 at "Research"
DOI: 10.34133/research.0075
Abstract: Monitoring the physiological changes of organelles is essential for understanding the local biological information of cells and for improving the diagnosis and therapy of diseases. Currently, fluorescent probes are considered as the most powerful tools… read more here.
Keywords: targeted fluorescent; artificial intelligence; design; organelle targeted ... See more keywords
Polydopamine-coated Au nanorods for targeted fluorescent cell imaging and photothermal therapy
Sign Up to like & getrecommendations! Published in 2019 at "Beilstein Journal of Nanotechnology"
DOI: 10.3762/bjnano.10.79
Abstract: Au nanorods (AuNRs) have attracted a great interest as a platform for constructing various composite core/shell nanoparticles for theranostics applications. However, the development of robust methods for coating AuNRs with a biocompatible shell of high… read more here.
Keywords: imaging photothermal; folate; aunr pda; photothermal therapy ... See more keywords