Enhancing the Bioactivity of Bicyclic Peptides Targeted to Grb7-SH2 by Restoring Cell Permeability
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DOI: 10.3390/biomedicines10051145
Abstract: The development of peptide inhibitors against intracellular targets depends upon the dual challenge of achieving a high affinity and specificity for the target and maintaining cellular permeability for biological activity. Previous efforts to develop bicyclic… read more here.
Keywords: cell; bicyclic peptides; grb7 sh2; targeted grb7 ... See more keywords