MR targeted imaging for the expression of tenascin‐C in myocardial infarction in vivo
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Magnetic Resonance Imaging"
DOI: 10.1002/jmri.25543
Abstract: To investigate the presence of viable myocardium in mice with acute myocardial infarction (MI) using a molecular targeted probe. read more here.
Keywords: targeted imaging; myocardial infarction; imaging expression; infarction ... See more keywords
Triarylboron-Based High Photosensitive Probes for Apoptosis Detection, Tumor-Targeted Imaging, and Selectively Inducing Apoptosis of Tumor Cells by Photodynamics.
Sign Up to like & getrecommendations! Published in 2022 at "Analytical chemistry"
DOI: 10.1021/acs.analchem.2c01364
Abstract: Herein, a series of triarylboron-based fluorescent probes were developed for distinguishing apoptosis from living cells and even necrosis. They also demonstrate high photosensitivity because they can produce detectable reactive oxygen species (ROS) under an ultra-low… read more here.
Keywords: apoptosis; targeted imaging; inducing apoptosis; apoptosis detection ... See more keywords
Targeted Imaging in Atherosclerosis.
Sign Up to like & getrecommendations! Published in 2022 at "Analytical chemistry"
DOI: 10.1021/acs.analchem.2c02644
Abstract: Atherosclerosis is a chronic inflammatory disease involved in plaque rupture, stroke, thrombosis, and heart attack (myocardial infarction), which is a leading cause of sudden cardiovascular events. In the past decades, various imaging strategies have been… read more here.
Keywords: atherosclerosis targeted; targeted imaging; imaging atherosclerosis; chemistry ... See more keywords
Two-Photon Excited FRET Dyads for Lysosome-Targeted Imaging and Photodynamic Therapy.
Sign Up to like & getrecommendations! Published in 2018 at "Inorganic chemistry"
DOI: 10.1021/acs.inorgchem.8b01581
Abstract: Two-photon excitable fluorescent dyes with integrated functions of targeted imaging and photodynamic therapy (PDT) are highly desired for the development of cancer theranostic agents. Herein, fluorescence resonance energy transfer (FRET) dyads, AceDAN-H2Por-Lyso (1a) and AceDAN-ZnPor-Lyso… read more here.
Keywords: photon; photodynamic therapy; targeted imaging; two photon ... See more keywords
Ferrocenyl-Triphenyltin Complexes as Lysosome-Targeted Imaging and Anticancer Agents.
Sign Up to like & getrecommendations! Published in 2019 at "Inorganic chemistry"
DOI: 10.1021/acs.inorgchem.8b03305
Abstract: In this paper, two ferrocenyl-triphenyltin complexes were synthesized and characterized. Complex 2 is constructed as new multifunctional therapeutic platform for lysosome-targeted imaging and displayed much higher cytotoxicity than its analogue 1 by the introduction of… read more here.
Keywords: targeted imaging; lysosome targeted; ferrocenyl triphenyltin; triphenyltin complexes ... See more keywords
Multivalent Supramolecular Assembly Based on a Triphenylamine Derivative for Near-Infrared Lysosome Targeted Imaging.
Sign Up to like & getrecommendations! Published in 2022 at "ACS applied materials & interfaces"
DOI: 10.1021/acsami.1c19698
Abstract: Near-infrared (NIR) targeted cell imaging has become a research hotspot due to the advantages of deeper tissue penetration, minimal interference from the background signals, and lower light damage. Herein, we report a multivalent supramolecular aggregate… read more here.
Keywords: assembly based; lysosome targeted; targeted imaging; near infrared ... See more keywords
In situ albumin tagging for targeted imaging of endothelial barrier disruption
Sign Up to like & getrecommendations! Published in 2025 at "Science Advances"
DOI: 10.1126/sciadv.ads4412
Abstract: The endothelial barrier (EB) is a critical component of the body’s homeostatic mechanisms, thus developing effective imaging techniques to visualize its integrity is essential. The EB disruption is accompanied by the alternations in permeability and… read more here.
Keywords: endothelial barrier; albumin tagging; disruption; targeted imaging ... See more keywords
Abstract CT104: MC1R imaging and histology in the targeted imaging of melanoma for alpha-particle radiotherapy (TIMAR1) trial
Sign Up to like & getrecommendations! Published in 2023 at "Cancer Research"
DOI: 10.1158/1538-7445.am2023-ct104
Abstract: Purpose: Melanocortin 1 receptor (MC1R) has been shown in animal models to be a target for effective radionuclide therapy. This first-in-human clinical trial studied the safety and biodistribution of two novel MC1R-targeted imaging tracers designed… read more here.
Keywords: melanoma; targeted imaging; mc1r; trial ... See more keywords
Abstract 4163: Improving the dynamic range of pH low insertion peptides for targeted imaging of pancreatic tumors
Sign Up to like & getrecommendations! Published in 2024 at "Cancer Research"
DOI: 10.1158/1538-7445.am2024-4163
Abstract: Objective: Current intraoperative imaging modalities such as near-infrared fluorescent imaging (NIR) or ultrasound are limited due to operator experience and depth, and targeted imaging of pancreatic tumors would be beneficial. However, specific pancreatic tumor biomarkers… read more here.
Keywords: cancer; targeted imaging; imaging pancreatic; pancreatic tumors ... See more keywords
VEGF receptor targeted imaging of angiogenic response to limb ischemia in diabetic vs. non-diabetic Yucatan minipigs
Sign Up to like & getrecommendations! Published in 2020 at "EJNMMI Research"
DOI: 10.1186/s13550-020-00626-0
Abstract: Background New therapies to treat diabetic peripheral artery disease (PAD) require target-specific non-invasive imaging modalities to follow efficacy. As a translational study, we performed targeted imaging of receptors for vascular endothelial growth factor (VEGF) in… read more here.
Keywords: diabetic yucatan; targeted imaging; response; yucatan minipigs ... See more keywords
Impact of PSMA-targeted imaging with 18F-DCFPyL-PET/CT on clinical management of patients (pts) with biochemically recurrent (BCR) prostate cancer (PCa): Results from a phase III, prospective, multicenter study (CONDOR).
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Clinical Oncology"
DOI: 10.1200/jco.2020.38.15_suppl.5501
Abstract: 5501Background: Current imaging modalities are inadequate for localizing and characterizing occult disease in men with BCR PCa, particularly in pts with low PSAs ( read more here.
Keywords: impact psma; targeted imaging; 18f dcfpyl; dcfpyl pet ... See more keywords