Applications of mass spectrometry-based targeted and non-targeted lipidomics.
Sign Up to like & getrecommendations! Published in 2018 at "Biochemical and biophysical research communications"
DOI: 10.1016/j.bbrc.2018.03.081
Abstract: Recent advances in mass spectrometry have expanded our knowledge of lipids and lipid metabolic pathways involved in many (patho)physiological events. Targeted and non-targeted lipidomics are powerful analytical strategies with distinct features, and a combination of… read more here.
Keywords: mass spectrometry; targeted non; targeted lipidomics; applications mass ... See more keywords
Combination of mass spectrometry-based targeted lipidomics and supervised machine learning algorithms in detecting adulterated admixtures of white rice.
Sign Up to like & getrecommendations! Published in 2017 at "Food research international"
DOI: 10.1016/j.foodres.2017.08.006
Abstract: The mixing of extraneous ingredients with original products is a common adulteration practice in food and herbal medicines. In particular, authenticity of white rice and its corresponding blended products has become a key issue in… read more here.
Keywords: rice; mass spectrometry; white rice; adulterated admixtures ... See more keywords
Targeted lipidomics reveals activation of resolution pathways in knee osteoarthritis in humans.
Sign Up to like & getrecommendations! Published in 2017 at "Osteoarthritis and cartilage"
DOI: 10.1016/j.joca.2017.01.018
Abstract: OBJECTIVE To investigate the presence of inflammation and resolution pathways in osteoarthritis (OA). DESIGN Tissues were obtained from knee OA patients and control rheumatoid arthritis (RA) patients. Cells in synovial fluid (SF) were visualized by… read more here.
Keywords: resolution; targeted lipidomics; lipidomics reveals; osteoarthritis ... See more keywords
Targeted Lipidomics and Transcriptomics Unveil Aberrant Lipid Metabolic Remodeling in Visceral and Subcutaneous Adipose Tissue under ER Stress.
Sign Up to like & getrecommendations! Published in 2025 at "Journal of proteome research"
DOI: 10.1021/acs.jproteome.4c00952
Abstract: Endoplasmic reticulum (ER) stress is known to impair the function of visceral adipose tissue (VAT) and subcutaneous adipose tissue (SAT), disrupting lipid metabolism. Despite the crucial role lipid plays in regulating adipose tissue function, the… read more here.
Keywords: stress; targeted lipidomics; subcutaneous adipose; vat sat ... See more keywords
Non-targeted lipidomics reveals the distinct metabolic mechanisms of nZnO and Zn ions in fish liver
Sign Up to like & getrecommendations! Published in 2025 at "Environmental Science: Nano"
DOI: 10.1039/d5en00160a
Abstract: The toxicity of environmental pollutants is often manifested through metabolic disruptions and damage to detoxification organs. However, current understanding is insufficient to explain the physiological response mechanisms of metabolically abnormal... read more here.
Keywords: targeted lipidomics; reveals distinct; distinct metabolic; metabolic mechanisms ... See more keywords
Comparative targeted lipidomics between serum and cerebrospinal fluid of multiple sclerosis patients shows sex and age-specific differences of endocannabinoids and glucocorticoids
Sign Up to like & getrecommendations! Published in 2024 at "Acta Neuropathologica Communications"
DOI: 10.1186/s40478-024-01864-2
Abstract: Multiple sclerosis (MS) is a complex chronic neuroinflammatory disease characterized by demyelination leading to neuronal dysfunction and neurodegeneration manifested by various neurological impairments. The endocannabinoid system (ECS) is a lipid signalling network, which plays multiple… read more here.
Keywords: age; multiple sclerosis; cerebrospinal fluid; targeted lipidomics ... See more keywords
Quantitative analysis of targeted lipidomics in the hippocampus of APP/PS1 mice employing the UHPLC-MS/MS method
Sign Up to like & getrecommendations! Published in 2025 at "Frontiers in Aging Neuroscience"
DOI: 10.3389/fnagi.2025.1561831
Abstract: Background Alzheimer’s disease (AD) is marked by the pathological features of amyloid-β plaque accumulation, as well as intracellular neurofibrillary tangles formation in the patients’ brain. Aberrant lipid metabolism is increasingly recognized as one of the… read more here.
Keywords: mice; quantitative analysis; method; hippocampus ... See more keywords
Integrated Quantitative Targeted Lipidomics and Proteomics Reveal Unique Fingerprints of Multiple Metabolic Conditions
Sign Up to like & getrecommendations! Published in 2022 at "Biomolecules"
DOI: 10.3390/biom12101439
Abstract: Aberrations in lipid and lipoprotein metabolic pathways can lead to numerous diseases, including cardiovascular disease, diabetes, neurological disorders, and cancer. The integration of quantitative lipid and lipoprotein profiling of human plasma may provide a powerful… read more here.
Keywords: targeted lipidomics; proteomics reveal; quantitative targeted; lipidomics proteomics ... See more keywords
Targeted Lipidomics and Inflammation Response to Six Weeks of Sprint Interval Training in Male Adolescents
Sign Up to like & getrecommendations! Published in 2023 at "International Journal of Environmental Research and Public Health"
DOI: 10.3390/ijerph20043329
Abstract: Lipids play an important role in coordinating and regulating metabolic and inflammatory processes. Sprint interval training (SIT) is widely used to improve sports performance and health outcomes, but the current understanding of SIT-induced lipid metabolism… read more here.
Keywords: targeted lipidomics; interval training; sprint interval; inflammatory markers ... See more keywords
Untargeted and Targeted Lipidomics Unveil Dynamic Lipid Metabolism Alterations in Type 2 Diabetes
Sign Up to like & getrecommendations! Published in 2024 at "Metabolites"
DOI: 10.3390/metabo14110610
Abstract: Background: Type 2 diabetes mellitus (T2DM) is a complex metabolic disorder with a growing body of evidence suggesting the central role of lipid metabolism in its pathogenesis. However, the dynamic changes in lipid metabolism across… read more here.
Keywords: t2dm; untargeted targeted; lipid metabolism; targeted lipidomics ... See more keywords
Application of Human Plasma Targeted Lipidomics and Analysis of Toxic Elements to Capture the Metabolic Complexities of Hypothyroidism
Sign Up to like & getrecommendations! Published in 2024 at "Molecules"
DOI: 10.3390/molecules29215169
Abstract: Background: Hypothyroidism (HT) affects millions worldwide and can lead to various lipid disorders. The metabolic complexity and the influence of toxic elements in autoimmune and non-autoimmune HT subtypes are not fully understood. This study aimed… read more here.
Keywords: application human; human plasma; toxic elements; targeted lipidomics ... See more keywords