Mitochondria-Targeted Lupane Triterpenoid Derivatives and Their Selective Apoptosis-Inducing Anticancer Mechanisms.
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DOI: 10.1021/acs.jmedchem.7b00679
Abstract: Betulin and betulinic acid have been widely studied for their anticancer activities. However, their further development is limited due to low bioavailability, poor aqueous solubility, and limited intracellular accumulation. In the present study, a triphenylphosphonium… read more here.
Keywords: lupane triterpenoid; mitochondria targeted; betulin betulinic; betulinic acid ... See more keywords