Uncovering Molecular Heterogeneity in the Kidney With Spatially Targeted Mass Spectrometry
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Physiology"
DOI: 10.3389/fphys.2022.837773
Abstract: The kidney functions through the coordination of approximately one million multifunctional nephrons in 3-dimensional space. Molecular understanding of the kidney has relied on transcriptomic, proteomic, and metabolomic analyses of kidney homogenate, but these approaches do… read more here.
Keywords: mass spectrometry; kidney; spatially targeted; targeted mass ... See more keywords
Absolute Quantification of Nav1.5 Expression by Targeted Mass Spectrometry
Sign Up to like & getrecommendations! Published in 2022 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms23084177
Abstract: Nav1.5 is the pore forming α-subunit of the cardiac voltage-gated sodium channel that initiates cardiac action potential and regulates the human heartbeat. A normal level of Nav1.5 is crucial to cardiac function and health. Over-… read more here.
Keywords: targeted mass; quantification; mass spectrometry; expression ... See more keywords